The wife of Evarts Graham, then head of surgery at Washington University, she had been an outstanding student at Bryn Mawr and later received a doctorate from the University of Chicago. At this time, prejudice against women in science was strong. Even a woman as gifted and privileged as Graham had difficulty finding a suitable position. Though Graham was a neurophysiologist, it was Gasser, rather than Erlanger (then head of physiology), who gave her a position. In subsequent publications Gasser referred to her simply as H. T. Graham. They collaborated on five articles, two dealing with pharmacology. Graham later did important independent studies on nerve function and went on to very original work on histamine.